The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking, homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers.Here, we att nighthawk hotspot identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-throughput screening assay.These are
Experimental observation on a model of free over flow spillway is used in this study.Three configurations of baffle placement are used in the experiment.The energy along the flow over the spillway were calculated based on measured flow depth and discharge during the experiment.Variations of flow depth and discharge were determined based on baffle h
BackgroundOral care is important to prevent buccal and systemic infections after an acquired brain injury (ABI).Despite recent advancements in the development of ABI clinical practice guidelines, recommendations for specific clinical processes and actions to attain adequate oral care often lack information.ObjectiveThis systematic review will (1) i
Erectile dysfunction (ED) is an inability to attain or maintain adequate penile erection for successful vaginal intercourse, leading to sexual and relationship dissatisfaction.To combat ED, various surgical and non-surgical approaches have been developed in the past to restore erectile functions.These therapeutic interventions exhibit significant i
Abstract When argon is used as a protecting gas in the fabrication or working environment of a nanodevice, absorption of some argon atoms onto the surface of the device lead to different responses.In this work, the rotation of the rotor in a carbon nanotube (CNT)-based rotary nanomotor in argon environment is investigated.In the rotary nanomotor, t